Introduction The PiSZ genotype results in less severe deficiency of alpha-1 antitrypsin (AAT) than PiZZ. Less is known about phenotypic and prognostic features. Methods We studied 699 PiZZ, 126 PiSZ ...
Correspondence to Professor Wim Janssens, Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven 3000, Belgium; wim.janssens{at}uzleuven.be Rationale Estimating the ...
Background Chronic Obstructive Pulmonary Disease (COPD) is associated with persistent airway inflammation, which may be driven by an imbalance between pro-inflammatory macrophages and dysfunctional ...
Background Despite progress in TB control in low-burden countries like England and Wales, there are still diagnostic delays. Molecular testing and/or whole-genome sequencing (WGS) provide more rapid ...
Department of Respiratory Medicine, St James’s University Hospital, Leeds LS9 7TF, UK Correspondence to: Dr P K Plant, Department of Respiratory Medicine, Level 7, Gledhow Wing, St James’s University ...
Oral montelukast in acute asthma exacerbations: a randomised, double-blind, placebo-controlled trial
1 Department of Respiratory Medicine, Norfolk & Norwich University Hospital, Norwich, UK 2 School of Medicine Health Policy & Practice, University of East Anglia, Norwich, UK Correspondence to Dr ...
1 School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, Norfolk, UK 2 Directorate of Medicine, Norfolk and Norwich University Hospital, Norwich, Norfolk, UK ...
Chronic cough or cough that lasts more than 8 weeks, once a chest x-ray and spirometry are confirmed normal, is caused by an alteration in a section of the route between peripheral receptors, mainly ...
2 Guy's and St Thomas' Foundation NHS Trust, London, UK 3 Greenwich Primary Care Trust, London, UK 4 Croydon Primary Care Trust, London, UK Background The COPD (chronic obstructive pulmonary disease) ...
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